Production Scientist

Department

Bioproduction

Location

San Diego, CA

Job Type

Full Time

ID #

1234556



 Cue Health Inc. is seeking to hire a full-time Production Scientist. Performs manufacturing techniques and/or methodologies to create products or processes, optimize current products or processes, and supports the transfer and scale up efforts of new products or processes from laboratory development to operations units. Supports the development, optimization, confirmation of processes, and validation and manufacturing of products. Utilizes bio-analytical methods (analytical chemistry, biochemistry, biotechnology, immunology, microbiology, molecular biology, or virology), independently or through collaboration with internal departments or contract labs, to provide analysis and testing support to bioprocessing projects, to aid in troubleshooting biologic quality controls (BioQC) and manufacturing issues, and/or to improve analyses used in products and bring in innovative chemical tests. 

What We’re Looking For

Responsibilities:

  • Perform manufacturing processes according to GMP documentation 

  • Perform analytical biochemistry for QA/QC of proteins 

  • Exercise considerable judgment and take initiative required to resolve problems and make recommendations 

  • Document experimental data, presenting data, conclusions and interpretations 

  • Follow established protocols and good laboratory practices

  • Purification of targets using AKTA FPLC 

  • Characterization of proteins by SDS-PAGE, Western blot, Nanodrop, HPLC, and additional methods as necessary 

  • Protein processing by dialysis, TFF and/or UFDF 

  • Maintenance of lab equipment (AKTA, HPLC, Microfluidizer, etc.) 

  • Responsible for troubleshooting non-conforming products to identify root cause. 

  • Conduct validation studies and shelf life studies as assigned

  • Review all operations documentation for technical content, accuracy, and completion in accordance with GMP 

Requirements:

  • BS degree in Biology, Chemistry, Molecular Biology or related field; MS preferred 

  • 4+ years experience in a lab environment for assay development or molecular biology

  • Proficient in downstream purification using the Unicorn system with AKTA instruments

  • Experience in process development, validation and implementation

  • Experience with E. coli-based protein expression a plus

  • Experience with fermenters and industrial experience are a plus

  • IVD experience preferred

  • Knowledge of GMP and GDP lab practices

  • Excellent verbal and written communication skills

  • Experience in characterization of proteins by SDS-PAGE, Western blot, Nanodrop, and HPLC

  • Experience in TFF (ultra-filtration, diafiltration), depth filtration and chromatography

  • Experience handling non-conformance and deviations


As part of Cue, you will:

Be instrumental in the mechanical design and development of Cue Health Inc’s cartridges.


Where you’ll work

You will work in a modern open office located in Sorrento Valley in San Diego, CA, with a lot of natural light. As an early employee your contribution will set the pace and have an impact in Cue’s future. Your work and ideas will be valued and respected, and we hope you will find enjoyment working with a great team on such an innovative device.


Perks within Cue culture

  • New computer equipment

  • Unlimited snacks

  • Competitive salary

  • Stock options